Batten disease is the common name for a group of lysosomal storage disorders called neuronal ceroid lipofuscinoses. There are 14 forms of the disease, and they primarily affect the eyes and the central nervous system. The diseases can be classified into four groups: infantile, late-infantile, juvenile, and adult-onset forms. Patients commonly present progressive cognitive and visual impairments, epileptic seizures, and deterio  Read More

Batten-mayou syndrome is an inherited metabolic disorder. It is passed down through families, thereby triggering a genetic mutation in an individual. The batten-mayou syndrome is evident to affect the cell’s competency to break down cellular waste, thereby, eliminating it from the body. When the body is unable to get rid of the sugars, lipids and proteins, they start accumulating, in turn, affecting the nervous system an  Read More

Huntington's disease is a genetic, progressive, neurodegenerative disorder characterized by the gradual development of involuntary muscle movements affecting the hands, feet, face, and trunk and progressive deterioration of cognitive processes and memory (dementia). Neurologic movement abnormalities may include uncontrolled, irregular, rapid, jerky movements (chorea) and athetosis, a condition characterized by relatively slow, writhing involun  Read More

Fahr's syndrome, familial idiopathic basal ganglia calcification, and primary familial brain calcification are further names for Fahr's disease. It is a very uncommon neurological condition marked by bilateral calcifications of certain brain regions. Fahr's disease typically affects people in their 40s and 50s, though it can also strike children or teenagers. The prevalence of the disease is lower than 1 in 1,000,000. There is a paucity of mol  Read More

Risk factors of Fahr’s disease: 1. Fahr's disease is a hereditary genetic condition marked by abnormal calcium deposits in parts of the brain that regulate movement. 2. Basal ganglia, cerebral, and cortical regions (parts of the brain) have calcium deposits that cause atrophy. 3. Motor and mental problems result from the considerable neuron (brain cell) loss caused by this mineral deposit.  Read More

Huntington's disease is a genetic, progressive, neurodegenerative disorder characterized by the gradual development of involuntary muscle movements affecting the hands, feet, face, and trunk and progressive deterioration of cognitive processes and memory (dementia). Neurologic movement abnormalities may include uncontrolled, irregular, rapid, jerky movements (chorea) and athetosis, a condition characterized by relatively slow, writhing involun  Read More

Familial idiopathic basal ganglia calcification (FIBGC) is a rare neurological disorder characterized by the presence of abnormal calcium deposits (calcifications) of unknown cause. Associated symptoms include progressive deterioration of cognitive abilities (dementia), loss of contact with reality (psychosis), mood swings and loss of acquired motor skills. As the condition progresses, paralysis may develop that is associated with increased mu  Read More

The extremely rare cerebral neurological condition known as Klüver-Bucy syndrome is characterized by damage to both temporal lobes, impairments in memory, social and sexual functioning, and odd behaviors. 1. The impulse to examine everything, excessive oral propensities, hypermetamorophobia, memory loss, emotional changes, exaggerated sexual behavior, apathy, placidity, visual distractibility, and visual agno  Read More

Binswanger disease is a progressive neurological disorder caused by arteriosclerosis and thromboembolism affecting the blood vessels that supply the white-matter and deep structures of the brain (basal ganglia and thalamus). Most patients experience progressive loss of memory and intellectual abilities (dementia), urinary urgency or incontinence, and an abnormally slow, shuffling, unsteady pattern of walking, usually over a 5-10 year period. D  Read More

Subacute sclerosing panencephalitis (SSPE) is a progressive neurological condition marked by brain inflammation (encephalitis). The sickness may arise as a result of measles virus reactivation or an improper immune response to the measles virus. SSPE typically manifests itself between two and ten years after the first viral infection. Memory loss, impatience, seizures, involuntary muscle movements, and/or behavioral abnormalit  Read More

Binswanger disease is a progressive neurological disorder caused by arteriosclerosis and thromboembolism affecting the blood vessels that supply the white-matter and deep structures of the brain (basal ganglia and thalamus). Most patients experience progressive loss of memory and intellectual abilities (dementia), urinary urgency or incontinence, and an abnormally slow, shuffling, unsteady pattern of walking, usually over a 5-10 year period. D  Read More

Metachromatic leukodystrophy, the most common form of leukodystrophy, is a rare inherited neurometabolic disorder affecting the white matter of the brain (leukoencephalopathy). It is characterized by the accumulation of a fatty substance known as sulfatide (a sphingolipid) in the brain and other areas of the body (i.e., liver, gall bladder, kidneys, and/or spleen). The fatty protective covering on the nerve fibers (myelin) is lost from areas o  Read More

Binswanger disease is a progressive neurological disorder caused by arteriosclerosis and thromboembolism affecting the blood vessels that supply the white-matter and deep structures of the brain (basal ganglia and thalamus). Most patients experience progressive loss of memory and intellectual abilities (dementia), urinary urgency or incontinence, and an abnormally slow, shuffling, unsteady pattern of walking, usually over a 5-10 year period. D  Read More